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MS-GRADE ENZYME

OA Lys-C, MS Grade

Sequencing-grade Endoproteinase Lys-C, quality-controlled and lyophilized for LC-MS proteomics workflows.

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Reliable C-Terminal Lysine Cleavage

OA Lys-C is sequencing-grade Endoproteinase Lys-C prepared for mass spectrometry. It cleaves specifically at the C-terminal side of lysine residues, remains active under denaturing conditions, and pairs with trypsin or Lys-N for expanded proteome coverage. Lyophilized from LC-MS-compatible buffer — no clean-up required. Certificate of Analysis with every lot.

Product Features

Lot-Level Confidence

Certificate of Analysis included with every lot for traceable, quality-controlled performance.

LC-MS Ready

Lyophilized from LC-MS-compatible buffer. Reconstitute and use with no additional clean-up.

Made in USA

Ships from Tucker, Georgia within 24–48 hours for in-stock orders.

Stable Storage

Store at -20°C and protect from moisture to preserve reagent performance.

Applications

Denaturing Digestion Workflows

Maintains activity under denaturing conditions to support efficient cleavage of complex proteins before LC-MS analysis.

Sequential Digestion

Pair with trypsin for improved digestion completeness or with Lys-N for complementary lysine-directed peptide sets.

Expanded Proteome Coverage

Use C-terminal lysine specificity as an orthogonal digestion strategy for deeper protein characterization.

Build a Complementary Digestion Strategy

Pair OA Lys-C with Lys-N in our matched Mirror Digestion Kit.

Explore the Mirror Kit