LysN Enzyme: Now Available

Premium N-terminal lysine protease for advanced proteomics research

Finally, a reliable source for premium LysN enzyme. Purified from mushrooms for exceptional performance in bottom-up proteomics, and protein characterization.

In Stock & Ready to Ship! – Ships within 24-48 hours

Why Choose Our LysN?

Exceptional purity and performance for demanding proteomics applications

N-Terminal Specificity

Cleaves at lysine residues on the N-terminal side, providing complementary coverage to trypsin and unique peptide patterns.

Aβ Biomarker Essential

Lys-N digestion overcomes the challenges of measuring the N- and C-terminal regions of Aβ and is essential for sensitive LC-MS/MS quantification of Aβ40 and Aβ42 in CSF and blood biomarker assays.

Enhanced DIA Proteomics

Peptides with greater ion mobility spread improve data-independent acquisition (DIA) proteomics performance and coverage.

Reliable Supply

No more searching for scarce suppliers. We maintain consistent inventory with fast shipping directly from our facility.

Premium Quality

Purified from mushrooms using proprietary methods. Rigorously tested for activity to ensure reproducible results.

Complementary Coverage

Different cleavage pattern than trypsin yields unique peptides for improved protein characterization and sequence coverage.

The LysN Advantage

N-term
Lysine Cleavage
24-48h
Shipping Time
100%
Tested Batches

Key Applications

Proven performance across critical proteomics workflows

Aβ Biomarker Assays

Lys-N digestion overcomes the challenges of measuring the N- and C-terminal regions of Aβ and is essential for sensitive LC-MS/MS quantification of Aβ40 and Aβ42 in CSF and blood biomarker assays.

Data-Independent Acquisition (DIA)

LysN-generated peptides show enhanced ion mobility spread, improving peak separation and identification confidence in DIA mass spectrometry workflows.

Protein Characterization

Complementary to trypsin digestion. Generate different peptide sets for comprehensive protein sequence coverage and post-translational modification mapping.

Difficult-to-Digest Proteins

Alternative cleavage strategy for proteins with limited lysine or arginine residues in specific regions. Improves coverage of challenging protein segments.

Bottom-Up Proteomics

Reliable enzyme for shotgun proteomics experiments. Consistent performance across diverse sample types including plasma, tissue, and cell lysates.

Quantitative Proteomics

Compatible with label-free and labeled quantification methods including TMT, iTRAQ, and SILAC for accurate protein quantitation.

Our Products

Complete solutions for advanced proteomics workflows

In Stock
Enzyme

Lys-N Protease - 20 µg

Premium Lys-N proteases for N-terminal lysine cleavage. SKU: LYSN-20

  • Purified from mushrooms
  • N-terminal lysine specificity
  • Tested for activity
In Stock
Enzyme

Lys-N Protease - 5x20 µg

Premium Lys-N proteases for N-terminal lysine cleavage. SKU: LYSN-100

  • Purified from mushrooms
  • N-terminal lysine specificity
  • Tested for activity
Custom Orders

Request a Quote

Custom enzyme sizes and aliquoting to suit your needs. Larger quantities available.

  • Custom aliquot sizes
  • Larger quantities available
  • Purchase orders accepted
View All Products

Ready to Advance Your Research?

Need a purchase order or custom quantities? We're here to help.

Request a Quote
LysN cleaves on the N-terminal side of lysine!
Mushy - Omic Adventures Mascot